Advanced Thermal Therapeutics

References at bottom of page

Why OcuTherm® became obsessive about
each detail of eye compress therapy.

Discomfort from chronic eye conditions can contribute to “vicious cycles” of unremitting eye pain, and even to depression, as eye discomfort overloads the nervous system.

However, patients who are empowered to create positive sensory input may be better able to override the negative pain signals from the eye region, and restore balance to their systems.

We designed the OcuTherm System to optimize the most important sensory elements in eye compress therapy, including:

  • Evenly-Distributed Feeling of the eye compress across both eyes

  • Sensory Touch and Appearance of all materials, especially those that contact the skin of the eyelids and face

  • Precise Conformation of each treatment to the eyelid contour

  • Thermal Consistency of OcuTherm Gel, whether hot, cool, or cold

Our aim is to deliver positive sensory input to a multitude of sensory receptors in the ocular, periocular, and periorbital regions, giving users a fighting chance against the “vicious cycle” of chronic pain.

Discomfort from chronic dry eye can contribute to “vicious cycles” of unremitting eye pain, and even to depression, as eye discomfort overloads the nervous system.

However, patients who are empowered to create positive sensory input may be better able to override the negative pain signals from the eye region, and restore balance to their systems.

We designed the OcuTherm System to optimize the most important sensory elements in eye compress therapy, including:

  • Evenly-Distributed Feeling of the eye compress across both eyes

  • Sensory Touch and Appearance of all materials, especially those that contact the skin of the eyelids and face

  • Precise Conformation of each treatment to the eyelid contour

  • Thermal Consistency of OcuTherm Gel, whether hot, cool, or cold

Our aim is to a multitude of sensory skin receptors in the ocular, periocular, and periorbital regions, helping patients break their “dry eye pain cycle.”

Discomfort from chronic dry eye can contribute to “vicious cycles” of unremitting eye pain, and even to depression, as eye discomfort overloads the nervous system.

However, patients who are empowered to create positive sensory input may be better able to override the negative pain signals from the eye region, and restore balance to their systems.

We designed the OcuTherm System to optimize the most important sensory elements in eye compress therapy, including:

  • Evenly-Distributed Feeling of the eye compress across both eyes

  • Sensory Touch and Appearance of all materials, especially those that contact the skin of the eyelids and face.

  • Precise Conformation of each treatment to the eyelid contour

  • Thermal Consistency of OcuTherm Gel, whether hot, cool, or cold

Our aim is to a multitude of sensory skin receptors in the ocular, periocular, and periorbital regions, helping patients break their “dry eye pain cycle.”

References

Nolano M, Provitera V, Crisci C, et al. Quantification of myelinated endings and mechanoreceptors in human digital skin. Ann Neurol. 2003 Aug;54(2):197 205.

Marfurt CF, Cox J, Deek S, Dvorscak L. Anatomy of the human corneal innervation. Exp Eye Res. 2010 Apr;90(4):478 92.

Schiffman RM, Walt JG, Jacobsen G et al. Utility assessment among patients with dry eye disease. Ophthalmology. 2003 Jul;110(7):1412 9.

Galor A, Levitt RC, Felix ER, Martin ER, Sarantopoulos CD. Neuropathic ocular pain: an important yet under evaluated feature of dry eye. Eye 29:301–312.

Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain 2011;152(3 Suppl):S2-15.

Crane AM, Levitt RC, Felix ER, Sarantopoulos KD, McClellan AL, Galor A. Patients with more severe symptoms of neuropathic ocular pain report more frequent and severe chronic overlapping pain conditions and psychiatric disease. Br J Ophthalmol. 2017 Feb;101(2):227-231.

Galor A, Batawi H, Felix ER, Margolis TP, Sarantopoulos KD, Martin ER, Levitt RC. Incomplete response to artificial tears is associated with features of neuropathic ocular pain. Br J Ophthalmol 2016 100:745–749

Ongun N, Ongun GT. Is gabapentin effective in dry eye disease and neuropathic ocular pain? Acta Neurol Belg. 2019 May 27.

Chinwuba I, Tsui E, Mitry M, et al. The OcuTherm System, a Novel At-Home Eyelid Thermal Treatment Device – A 4-Week Clinical Study. Invest. Ophthalmol. Vis. Sci. 2017;58(8):2684.

Mendell LM. Constructing and Deconstructing the Gate Theory of Pain. Pain. 2014 February ; 155(2): 210–216.

Mouraux A, Diukova A, Lee MC, Wise RG, Iannetti GD. NeuroImage 54 (2011) 2237–2249. A multisensory investigation of the functional significance of the pain matrix.